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R2G mutation in the TUBB4a gene DYT4, encoding the isoform a of b Tubulin has been identified by exome sequencing Hersheson et al. , 2012. Molecular screening of 394 phenotypically similar patients identified a novel mutation p. A271T in one case Lohmann et al. , 2013. Mutations in CIZ1 DYT23, CDKN1A interacting zinc finger protein 1, ANO3 DYT24, Anoctamin 3, encoding a calcium gated chloride channel highly expressed in the striatum, and GNAL DYT25, guanine nucleotide binding protein, alpha activating activity polypeptide, olfactory type, have been identified in families with juvenile adult onset cervical or cranial cervical dystonia and in a few sporadic cases with similar phenotypes Charlesworth et al. , 2012; Xiao et al. , 2012; Fuchs et al. , 2013. In particular, GNAL mutations were detected in additional 6 out of 39 families 15%, suggesting they could represent a major cause of adult onset cranial cervical dystonia PTD. Other AD PTD loci have been described in isolated familial cases.


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Students involved in these programs will be informed of what is possible and what conditions are in place to safely continue learning in these areas. NOTE Please note however, that all items listed above are correct as at the time of publishing this newsletter, however are subject to change at any time. The September meeting of the Newcomb Secondary College Council took place remotely on the last Thursday of term 3. Among the items discussed were the return to school in week 2, the new building works which are about to commence, as well as uniform suppliers. Firstly, we hope you are all well and have enjoyed a great holiday break!We certainly look forward to hearing all of the stories and highlights. As you well know, the landscape is constantly changing regarding COVID 19. Pleasingly however, the changes that are currently happening are of a positive nature offering us all the opportunity to return closer to a life that we would deem to be more normal than that of recent times. Information is coming to hand almost each day regarding how schools must operate. We will provide you with as much information as possible as it comes to hand. 2. Essential Assessments will be undertaken for specific subjects.



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I understand the importance of being able to find semantic information in our content and I realize that a semantic structure makes a huge difference in search engine accuracy and when scraping, scavenging. I dont think that we should avoid semantic declarations, but I also dont think it should be HTML. Or at least it should be an extension to HTML called HTSL or something. I wish that HTML had been purified to HT followed by the intended use of said Hyper Text: Markup Language, or Semantic Language. Then in the future, when we have device specific contexts or audience relative contexts, we dont have to rewrite the entire spec, we add a flavor of HyperText and call it Contextual Language. But to extend the HT used to layout a document by adding new arbitrary elements named conspicuously like a media format that is quickly disappearing seems dirty and short sited to me. In other words, I would much prefer to have where the markup language provides the structure, the various other aspects are added to the markup. Then generalize the markup language to include things like: or or or or . A semantic element or context element or style element seems so much more reasonable. And when complaining about bulky markup by ADDing these elements, I say that device specific browsers could provide an option to recompile the markup to avoid the extra semantics and contexts and whatever they come up with a year from now. If your reader device doesnt need the extra contexts or cant really use the semantics, the device can easily get rid of it.



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